[PDF][PDF] A novel insight into the nature of modified low-density lipoproteins and their role in atherosclerosis

DA Kashirskikh, S Guo, S Panyod, NR Chicherina… - Vessel Plus, 2023 - researchgate.net
Modified LDLs can be found in atherosclerotic lesions and in … The separation of lipoproteins
into classes made it possible … of desialylated LDL was isolated from the atherogenic serum of …

Proatherogenic sialidases and desialylated lipoproteins: 35 years of research and current state from bench to bedside

A Mezentsev, E Bezsonov, D Kashirskikh, MS Baig… - Biomedicines, 2021 - mdpi.com
density lipoproteins and decreases the anti-atherogenic … in the blood to promote the formation
of atherosclerotic plaques [1]. … of atherosclerosis and the modified atherogenic low-density

We Must Abandon the Myth: Oxidized Low-density Lipoprotein is not a Lipoprotein that Plays a Key Role in Atherogenesis

AN Orekhov - Current Medicinal Chemistry, 2024 - ingentaconnect.com
… tion, such as desialylated LDL, was an order of magnitude stronger. At least 3 forms of
atherogenic modified lipoproteins were isolated from the blood of atherosclerotic patients using …

Increased APOE glycosylation plays a key role in the atherogenicity of L5 lowdensity lipoprotein

LY Ke, HC Chan, CC Chen, CF Chang… - The FASEB …, 2020 - Wiley Online Library
… primary prevention for atherosclerotic cardiovascular disease (… subfractions isolated from
human native low-density lipoproteins (… Modification of low density lipoprotein by desialylation

Thirty-five-year history of desialylated lipoproteins discovered by Vladimir Tertov

V Glanz, EE Bezsonov, V Soldatov, AN Orekhov - Biomedicines, 2022 - mdpi.com
… of modified low-density lipoproteins (LDL) in atherosclerosis … to the appearance of
atherosclerotic lesions in arterial walls. … the ApoB protein of native LDL isolated from the patients

Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating LowDensity Lipoproteins and Increasing Their Uptake by Macrophages

EP Demina, V Smutova, X Pan, A Fougerat… - Journal of the …, 2021 - Am Heart Assoc
atherosclerosis starts with an uptake of atherogenic modified … fatty streaks and eventually
atheromatous plaques. Increased … blood macrophages and smooth muscle cells isolated from …

Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis

A Pirillo, M Svecla, AL Catapano… - Cardiovascular …, 2021 - academic.oup.com
… Protein glycosylation is a post-translational modification … ALG6-CDG patients showed an
increased low density lipoprotein … no signs of preclinical atherosclerotic lesions as determined …

Prospects for the use of sialidase inhibitors in anti-atherosclerotic therapy

IA Sobenin, AM Markin, VY Glanz… - Current Medicinal …, 2021 - ingentaconnect.com
desialylation is in vivo lipoprotein atherogenic modification … enzyme was isolated from
serum by affinity chromatography. … acid from native LDL, LDL, very lowdensity lipoprotein (VLDL) …

[HTML][HTML] Lipoprotein sialylation in atherosclerosis: lessons from mice

L Yu, J Peng, C Mineo - Frontiers in Endocrinology, 2022 - frontiersin.org
low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), and it contains a number of
glycosylation sites, majority of which are modified … did not reduce the atherosclerotic plaque …

Proteomic studies on apoB‐containing lipoprotein in cardiovascular research: A comprehensive review

E Gianazza, B Zoanni, A Mallia… - Mass Spectrometry …, 2023 - Wiley Online Library
… -density lipoprotein (HDL). The main reason is that more than … of atherogenic modifications
of sdLDL in the blood plasma. … Healthy normolipidemic subjects and atherosclerotic patients